The Scottsdale Museum of Contemporary Art is located right next to Old Town Scottsdale, Arizona at Drinkwater and 2nd Street. It is on the Scottsdale Civic Center Mall, next to the Scottsdale Center for the Performing Arts. Here's the address:
7374 East Second Street
Scottsdale, AZ 85251
Here is a map and directions to the Scottsdale Civic Center Mall. The closest parking is the Public Parking Garage at Wells Fargo and 2nd Street. Parking is free. If that lot is full, you can try to park at the Scottsdale Public Library Parking Garage, also free, on the east side of Drinkwater Blvd. SMoCA is also accessible by free public transportation, the Scottsdale Trolley. That may be your best bet if you are visiting the museum on a Thursday evening in conjunction with the weekly Scottsdale Art Walk.
SMoCA doesn't have its own cafe, but there are dining establishments on the Mall and in Old Town Scottsdale within walking distance from the museum.
SMoCA Factoid: All five galleries at SMoCA rotate exhibitions three times per year in fall, spring and summer.